817586-01-9
817586-01-9
Chemical Structure
FTI-2148 diTFA
- CAS No.: 817586-01-9
- Formula:C28H30F6N4O7S
- Molecular Weight:680.62
IUPAC Name: (5-((((1H-imidazol-4-yl)methyl)amino)methyl)-2'-methyl-[1,1'-biphenyl]-2-carbonyl)-L-methionine compound with 2,2,2-trifluoroacetic acid (1:2)
InChIKey: SEWRURJXMIPHFK-IKXQUJFKSA-N
SMILES: CSCC[C@@H](C(O)=O)NC(C1=CC=C(CNCC2=CNC=N2)C=C1C3=CC=CC=C3C)=O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Biological Activity: FTI-2148 diTFA is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 1.4 nM and 1.7 μM, respectively[1].
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FTI-2148 diTFA | FTI-2148 diTFA is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 1.4 nM and 1.7 μM, respectively. | |||||||||||||||||||||
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References
Keywords
