83016-63-1
83016-63-1
Chemical Structure
DBNBS
- CAS No.: 83016-63-1
- Formula:C6H3Br2NO4S
- Molecular Weight:344.97
InChIKey: NTFXNXQDQBCQSU-UHFFFAOYSA-N
SMILES: O=NC1=C(C=C(S(=O)(O)=O)C=C1Br)Br
Biological Activity: DBNBS is a radical scavenger. DBNBS undergoes non-radical nucleophilic addition to bind directly to cysteine (e.g., Cys-34 of BSA) to form a hydroxylamine, which is subsequently oxidized to produce an artifact spin adduct signal. DBNBS can be used for detecting biological free radicals[1].
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DBNBS | DBNBS is a radical scavenger. DBNBS undergoes non-radical nucleophilic addition to bind directly to cysteine (e.g., Cys-34 of BSA) to form a hydroxylamine, which is subsequently oxidized to produce an artifact spin adduct signal. DBNBS can be used for detecting biological free radicals. | |||||||||||||||||||||
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References
- [1]. Silvester JA, et al. A study of photochemically-generated protein radical spin adducts on bovine serum albumin: the detection of genuine spin-trapping and artefactual, non-radical addition in the same molecule. Redox report : communications in free radical research. 1997 Aug;3(4):225-31. [Content Brief]
