85375-15-1
85375-15-1
Chemical Structure
SKF89976A hydrochloride
Synonym(s): d,l-SKF89976A hydrochloride
- CAS No.: 85375-15-1
- Formula:C22H26ClNO2
- Molecular Weight:371.90
IUPAC Name: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride
InChIKey: SNGGBKYQZVAQKA-UHFFFAOYSA-N
SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O.[H]Cl
Biological Activity: SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively.
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SKF89976A hydrochloride | 98.73% | SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. | ||||||||||||||||||||
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SKF89976A hydrochloride (Standard) | ≥98% | SKF89976A (hydrochloride) (Standard) is the analytical standard of SKF89976A (hydrochloride) (HY-100228A). This product is intended for research and analytical applications. SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-100228SKF 89976A -
Similarity Score 0.71
HY-182944GATT-44 -
Similarity Score 0.66
HY-101724ReN-1869 hydrochloride -
Similarity Score 0.65
HY-124423ReN 1869 -
Similarity Score 0.62
HY-106870Pibaxizine -
Similarity Score 0.59
HY-106487Pridefine -
Similarity Score 0.59
HY-W742725Citalopram impurity 11 -
Similarity Score 0.59
HY-B0696ATiagabine hydrochloride -
Similarity Score 0.58
HY-16171RDiphenmanil methylsulfate (Standard) -
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