858770-07-7
858770-07-7
Chemical Structure
cGAS-IN-1
- CAS No.: 858770-07-7
- Formula:C18H19NO8
- Molecular Weight:377.35
InChIKey: RMQTZPUNTDZXLX-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C(C)=C(CCC(N(CC(O)=O)CC(O)=O)=O)C(O2)=O)C=C1
Biological Activity: cGAS-IN-1 (Compound C20) is a cyclic GMP-AMP synthase (cGAS) inhibitor with IC50s of 2.28 μM (human cGAS, h-cGASFL) and 1.44 μM (mouse cGAS, m-cGASCD). cGAS-IN-1 can be used for the studies of autoimmune diseases and chronic inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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cGAS-IN-1 | 98.21% | cGAS-IN-1 (Compound C20) is a cyclic GMP-AMP synthase (cGAS) inhibitor with IC50s of 2.28 μM (human cGAS, h-cGASFL) and 1.44 μM (mouse cGAS, m-cGASCD). cGAS-IN-1 can be used for the studies of autoimmune diseases and chronic inflammation. | ||||||||||||||||||||
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References
Keywords
