864814-88-0
864814-88-0
Chemical Structure
Resminostat
Synonym(s): RAS2410; 4SC-201
- CAS No.: 864814-88-0
- Formula:C16H19N3O4S
- Molecular Weight:349.40
IUPAC Name: (E)-3-(1-((4-((dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide
InChIKey: FECGNJPYVFEKOD-VMPITWQZSA-N
SMILES: O=C(NO)/C=C/C1=CN(S(=O)(C2=CC=C(CN(C)C)C=C2)=O)C=C1
Biological Activity: Resminostat (RAS2410; 4SC-201) is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM.
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Resminostat | 99.44% | Resminostat (RAS2410; 4SC-201) is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM. | ||||||||||||||||||||
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Keywords
