866127-80-2
866127-80-2
Chemical Structure
UR778Br
- CAS No.: 866127-80-2
- Formula:C20H20BrNO4
- Molecular Weight:418.28
InChIKey: JRUXICTUJPRUER-UHFFFAOYSA-N
SMILES: CCCCN1C(C(CC(C2=CC=CC=C2O)=O)(C3=C1C=CC(Br)=C3)O)=O
Biological Activity: UR778Br targets the GTPase-activating protein-related domain (GRD domain) of IQGAP1 proteins. UR778Br inhibits the proliferation of human acute myeloid leukemia (AML), arrests the cell cycle at the G2/M phase, and induces apoptosis. UR778Br inhibits colony formation of primary and AML cells, without significant impacts on normal bone marrow cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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UR778Br | 99.33% | UR778Br targets the GTPase-activating protein-related domain (GRD domain) of IQGAP1 proteins. UR778Br inhibits the proliferation of human acute myeloid leukemia (AML), arrests the cell cycle at the G2/M phase, and induces apoptosis. UR778Br inhibits colony formation of primary and AML cells, without significant impacts on normal bone marrow cells. | ||||||||||||||||||||
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References
Keywords
