867160-71-2
867160-71-2
Chemical Structure
Linsitinib
Synonym(s): OSI-906
- CAS No.: 867160-71-2
- Formula:C26H23N5O
- Molecular Weight:421.49
IUPAC Name: (1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol
InChIKey: PKCDDUHJAFVJJB-VLZXCDOPSA-N
SMILES: O[C@@]1(C)C[C@@H](C2=NC(C3=CC=C4C=CC(C5=CC=CC=C5)=NC4=C3)=C6C(N)=NC=CN62)C1
Biological Activity: Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC50s of 35 and 75 nM, respectively[1].
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Linsitinib | 99.90% | Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC50s of 35 and 75 nM, respectively. | ||||||||||||||||||||
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Linsitinib (Standard) | ≥98% | Linsitinib (Standard) is the analytical standard of Linsitinib. This product is intended for research and analytical applications. Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC50s of 35 and 75 nM, respectively. | ||||||||||||||||||||
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References
Keywords
