869898-86-2
Chemical Structure
Platencin
- CAS No.: 869898-86-2
- Formula:C24H27NO6
- Molecular Weight:425.47
IUPAC Name: 2,4-dihydroxy-3-(3-((2S,4aS,8S,8aR)-8-methyl-3-methylene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl)propanamido)benzoic acid
InChIKey: DWUHGPPFFABTIY-RLWZQHMASA-N
SMILES: O=C1C=C[C@]2(CC3)CC([C@@]3(C[C@]2([C@@]1(CCC(NC4=C(C(C(O)=O)=CC=C4O)O)=O)C)[H])[H])=C
Biological Activity: Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis. Platencin inhibits β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively) with IC50s of 1.95 and 3.91 μg/ml, respectively[1].
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Platencin | Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis. Platencin inhibits β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively) with IC50s of 1.95 and 3.91 μg/ml, respectively. | |||||||||||||||||||||
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Keywords
