870281-17-7
870281-17-7
Chemical Structure
PI3Kδ-IN-15
- CAS No.: 870281-17-7
- Formula:C21H16FN7O
- Molecular Weight:401.40
IUPAC Name: (S)-2-(1-((9H-purin-6-yl)amino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
InChIKey: BVUBLIHUYSRSFE-LBPRGKRZSA-N
SMILES: O=C1N(C2=CC=CC=C2)C([C@@H](NC3=C4N=CNC4=NC=N3)C)=NC5=C1C(F)=CC=C5
Biological Activity: PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PI3Kδ-IN-15 | 99.52% | PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα. | ||||||||||||||||||||
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References
Keywords
