894554-89-3
Chemical Structure
Deltazinone 1
- CAS No.: 894554-89-3
- Formula:C27H31N5O2
- Molecular Weight:457.57
IUPAC Name: 4-(3,4-dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)-N-(2-phenylpropyl)butanamide
InChIKey: HZNKNJCWLQLQMJ-UHFFFAOYSA-N
SMILES: CC1=CC=C(N2C(C)=C(C(C)=NN(CCCC(NCC(C)C3=CC=CC=C3)=O)C4=O)C4=N2)C=C1
Biological Activity: Deltazinone 1, a pyrazolopyridazinone, is a highly selective PDEδ inhibitor with a KD of 8 nM. Deltazinone 1 inhibits the PDEδ-Ras interaction. Deltazinone 1 shows a dose-dependent inhibitory response on proliferation in oncogenic KRas-dependent cell lines[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Deltazinone 1 | 98.79% | Deltazinone 1, a pyrazolopyridazinone, is a highly selective PDEδ inhibitor with a KD of 8 nM. Deltazinone 1 inhibits the PDEδ-Ras interaction. Deltazinone 1 shows a dose-dependent inhibitory response on proliferation in oncogenic KRas-dependent cell lines. | ||||||||||||||||||||
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Keywords
