895460-70-5
895460-70-5
Chemical Structure
BRD7586
- CAS No.: 895460-70-5
- Formula:C17H14ClN3O3S2
- Molecular Weight:407.89
IUPAC Name: 3-((4-chlorophenyl)sulfonyl)-N-(4-(pyridin-4-yl)thiazol-2-yl)propanamide
InChIKey: MLSIIIMAQNQEOV-UHFFFAOYSA-N
SMILES: O=C(CCS(=O)(C1=CC=C(C=C1)Cl)=O)NC2=NC(C3=CC=NC=C3)=CS2
Biological Activity: BRD7586 is a potent and selective Streptococcus pyogenes Cas9 (SpCas9) inhibitor. BRD7586 specifically engages SpCas9 but not Cas12a in cells and enhances SpCas9 specificity at multiple loci. BRD7586 inhibits SpCas9 at multiple genomic loci irrespective of the mode of SpCas9 delivery[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BRD7586 | 99.03% | BRD7586 is a potent and selective Streptococcus pyogenes Cas9 (SpCas9) inhibitor. BRD7586 specifically engages SpCas9 but not Cas12a in cells and enhances SpCas9 specificity at multiple loci. BRD7586 inhibits SpCas9 at multiple genomic loci irrespective of the mode of SpCas9 delivery. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.65
HY-47821WAY-655978 -
Similarity Score 0.64
HY-Q22471ROCK1-IN-1 -
Similarity Score 0.63
HY-153011ROCK-IN-5 -
Similarity Score 0.60
HY-110339RKI-1447 dihydrochloride -
Similarity Score 0.60
HY-15755RKI-1447 -
Similarity Score 0.59
HY-107209RKI-1313 -
Similarity Score 0.59
HY-124815CP-312 -
Similarity Score 0.57
HY-116420ROCK2-IN-8 -
Similarity Score 0.56
HY-115959Anticancer agent 34 -
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