CP-312
Based on 1 Customer Validation
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.
For research use only. We do not sell to patients.
- Purity: 99.18%
- CAS No.: 895470-67-4
- Formula: C16H12ClN3OS2
- Molecular Weight:361.87
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
CP-312 (10 µM; 2 h) exhibits good potency in protecting hiPSC-CMs from acute peroxide-induced cell death with EC50 = 6.7 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 895470-67-4
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Appearance Solid
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Molecular Weight 361.87
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Formula C16H12ClN3OS2
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Color Off-white to pink
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SMILES
O=C(NC1=NC(C2=NC=CC=C2)=CS1)CSC3=CC=C(Cl)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (276.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7634 mL | 13.8171 mL | 27.6342 mL | 69.0856 mL |
| 5 mM | 0.5527 mL | 2.7634 mL | 5.5268 mL | 13.8171 mL | |
| 10 mM | 0.2763 mL | 1.3817 mL | 2.7634 mL | 6.9086 mL | |
| 15 mM | 0.1842 mL | 0.9211 mL | 1.8423 mL | 4.6057 mL | |
| 20 mM | 0.1382 mL | 0.6909 mL | 1.3817 mL | 3.4543 mL | |
| 25 mM | 0.1105 mL | 0.5527 mL | 1.1054 mL | 2.7634 mL | |
| 30 mM | 0.0921 mL | 0.4606 mL | 0.9211 mL | 2.3029 mL | |
| 40 mM | 0.0691 mL | 0.3454 mL | 0.6909 mL | 1.7271 mL | |
| 50 mM | 0.0553 mL | 0.2763 mL | 0.5527 mL | 1.3817 mL | |
| 60 mM | 0.0461 mL | 0.2303 mL | 0.4606 mL | 1.1514 mL | |
| 80 mM | 0.0345 mL | 0.1727 mL | 0.3454 mL | 0.8636 mL | |
| 100 mM | 0.0276 mL | 0.1382 mL | 0.2763 mL | 0.6909 mL |
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