89622-90-2
89622-90-2
Chemical Structure
Brinazarone
Synonym(s): SR 33287
- CAS No.: 89622-90-2
- Formula:C25H32N2O2
- Molecular Weight:392.53
IUPAC Name: (4-(3-(tert-butylamino)propoxy)phenyl)(2-isopropylindolizin-3-yl)methanone
InChIKey: ZVRBFQSPBKYIAR-UHFFFAOYSA-N
SMILES: O=C(C1=C(C(C)C)C=C2C=CC=CN21)C3=CC=C(C=C3)OCCCNC(C)(C)C
Biological Activity: Brinazarone (SR 33287) is an inhibitor for acid lysosomal sphingomyelinase, and leads to cellular lipidosis. Brinazarone potentiates the cytotoxic effects of anti-Thy 1.2 AT15E RTA-IT on T2 cells and anti-CD5 T101 on CEM cells[1].
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Brinazarone | Brinazarone (SR 33287) is an inhibitor for acid lysosomal sphingomyelinase, and leads to cellular lipidosis. Brinazarone potentiates the cytotoxic effects of anti-Thy 1.2 AT15E RTA-IT on T2 cells and anti-CD5 T101 on CEM cells. | |||||||||||||||||||||
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References
Keywords
