897016-26-1
897016-26-1
Chemical Structure
KX2-361
Synonym(s): KX-02
- CAS No.: 897016-26-1
- Formula:C24H24FN3O2
- Molecular Weight:405.46
IUPAC Name: N-(3-fluorobenzyl)-2-(5-(4-morpholinophenyl)pyridin-2-yl)acetamide
InChIKey: CMKKPJNMYLOUCE-UHFFFAOYSA-N
SMILES: O=C(NCC1=CC=CC(F)=C1)CC2=NC=C(C3=CC=C(N4CCOCC4)C=C3)C=C2
Biological Activity: KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KX2-361 | 99.09% | KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell. | ||||||||||||||||||||
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KX2-361 (Standard) | ≥98% | KX2-361 (Standard) is the analytical standard of KX2-361 (HY-111187). This product is intended for research and analytical applications. KX2-361 (KX-02) is a Src-Kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-10340Tirbanibulin -
Similarity Score 0.68
HY-10340ARTirbanibulin dihydrochloride (Standard) -
Similarity Score 0.65
HY-10340BTirbanibulin Mesylate -
Similarity Score 0.57
HY-19713LJI308 -
Similarity Score 0.57
HY-10961RMomelotinib (Standard) -
Similarity Score 0.57
HY-146727JAK3-IN-11 -
Similarity Score 0.57
HY-757804-(2-(4-Morpholinophenylamino)pyrimidin-4-yl)benzoic acid -
Similarity Score 0.56
HY-169197D-688 -
Similarity Score 0.56
HY-W064657Momelotinib dihydrochloride -
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