898920-65-5
Chemical Structure
CLK8
- CAS No.: 898920-65-5
- Formula:C29H26N2O6
- Molecular Weight:498.53
IUPAC Name: 2-(2-((8,8-dimethyl-2-oxo-4-phenyl-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-5-yl)oxy)acetamido)benzamide
InChIKey: SVELPNHVEDZZRQ-UHFFFAOYSA-N
SMILES: O=C(COC1=C(C(C2=CC=CC=C2)=CC(O3)=O)C3=C(CCC(C)(C)O4)C4=C1)NC5=C(C(N)=O)C=CC=C5
Biological Activity: CLK8 is a potent and specific CLOCK inhibitor that can disrupt the interaction between CLOCK and BMAL1 and interfere with nuclear translocation of CLOCK. CLK8 can be used for the research of disorders associated with dampened circadian rhythms[1].
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CLK8 | 98.06% | CLK8 is a potent and specific CLOCK inhibitor that can disrupt the interaction between CLOCK and BMAL1 and interfere with nuclear translocation of CLOCK. CLK8 can be used for the research of disorders associated with dampened circadian rhythms. | ||||||||||||||||||||
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Keywords