Inophyllum B
Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica.
For research use only. We do not sell to patients.
- CAS No.: 41135-06-2
- Formula: C25H24O5
- Molecular Weight:404.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HIV-1 1.4 μM (IC50) |
Reverse Transcriptase 38 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | IC50 |
1.4 μM
Compound: 2a (inophyllum B)
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Anti-HIV activity against HIV-1 in Molt-4 cells using 7-day infective assay
Anti-HIV activity against HIV-1 in Molt-4 cells using 7-day infective assay
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[PMID: 7506311] |
| MOLT-4 | IC50 |
55 μM
Compound: 2a (inophyllum B)
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Tested for cytotoxicity in Molt-4 cells by XTT assay
Tested for cytotoxicity in Molt-4 cells by XTT assay
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[PMID: 7506311] |
Chemical Information
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CAS No. 41135-06-2
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Molecular Weight 404.46
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Formula C25H24O5
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SMILES
O[C@@H]1C2=C(O[C@@H]([C@H]1C)C)C(C=CC(C)(O3)C)=C3C(C(C4=CC=CC=C4)=C5)=C2OC5=O
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Synonyms
(+)-Inophyllum B
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Inophyllum B Related Classifications
HY-142074 Related Classifications
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