9001-47-2
9001-47-2
Chemical Structure
Glutaminase
Synonym(s): GLS
- CAS No.: 9001-47-2
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Glutaminase]
Biological Activity: Glutaminase is a metabolic enzyme. Glutaminase catalyzes the hydrolysis of glutamine to glutamate. Glutaminase isoenzymes are encoded by Gls and Gls2 genes. Proteins GLS and GLS2 have different kinetic, immunologic, and molecular characteristics. Glutaminase can be used in the research of cancer[1][2].
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Glutaminase | Glutaminase is a metabolic enzyme. Glutaminase catalyzes the hydrolysis of glutamine to glutamate. Glutaminase isoenzymes are encoded by Gls and Gls2 genes. Proteins GLS and GLS2 have different kinetic, immunologic, and molecular characteristics. Glutaminase can be used in the research of cancer. | |||||||||||||||||||||
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References
- [1]. Wang JB, et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 2010 Sep 14;18(3):207-19. [Content Brief]
- [2]. Matés JM, et al. Glutaminase isoenzymes in the metabolic therapy of cancer. Biochim Biophys Acta Rev Cancer. 2018 Dec;1870(2):158-164. [Content Brief]
Keywords
