913064-47-8
913064-47-8
Chemical Structure
ELN-441958
- CAS No.: 913064-47-8
- Formula:C29H29ClN4O2
- Molecular Weight:501.02
IUPAC Name: 7-chloro-2-(3-(9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecane-3-carbonyl)phenyl)isoindolin-1-one
InChIKey: ARYQHSWJGHCGJS-UHFFFAOYSA-N
SMILES: ClC1=C2C(CN(C3=CC=CC(C(N4CCC5(CCN(C6=CC=NC=C6)CC5)CC4)=O)=C3)C2=O)=CC=C1
Biological Activity: ELN-441958 is a potent, neutral, competitive and selective bradykinin B1 receptor antagonist with a Ki of 0.26 nM against native human bradykinin B1 receptor. ELN-441958 has high oral bioavailability, and has low CNS exposure in the mouse[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ELN-441958 | 99.17% | ELN-441958 is a potent, neutral, competitive and selective bradykinin B1 receptor antagonist with a Ki of 0.26 nM against native human bradykinin B1 receptor. ELN-441958 has high oral bioavailability, and has low CNS exposure in the mouse. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.50
HY-145257GABAA receptor agent 5 -
Similarity Score 0.48
HY-161638E3 Ligase Ligand-linker Conjugate 108 -
Similarity Score 0.48
HY-156257UNC9512 -
Similarity Score 0.47
HY-119368NPB -
Similarity Score 0.47
HY-125645M122 -
Similarity Score 0.47
HY-100605VU0483605 -
Similarity Score 0.47
HY-161640E3 Ligase Ligand-linker Conjugate 109 -
Similarity Score 0.47
HY-164441Anticancer agent 252 -
Similarity Score 0.46
HY-124701Filastatin -
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