924296-17-3
924296-17-3
Chemical Structure
DUB-IN-3
- CAS No.: 924296-17-3
- Formula:C16H9N5O
- Molecular Weight:287.28
IUPAC Name: (E)-9-((allyloxy)imino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
InChIKey: XLOXSIKLUAMDGU-RCCKNPSSSA-N
SMILES: C=CCO/N=C1C2=C(N=C(C#N)C(C#N)=N2)C3=CC=CC=C/13
Biological Activity: DUB-IN-3 (compound 22c) is a potent and selective inhibitor of the deubiquitinating enzyme USP8 with an IC50 value of 0.56 μM. DUB-IN-3 is promising for research of cancer, neurodegenerative diseases, inflammation, viral infection and cardiovascular disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
DUB-IN-3 | 99.00% | DUB-IN-3 (compound 22c) is a potent and selective inhibitor of the deubiquitinating enzyme USP8 with an IC50 value of 0.56 μM. DUB-IN-3 is promising for research of cancer, neurodegenerative diseases, inflammation, viral infection and cardiovascular disease. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.90
HY-50737ADUB-IN-2 -
Similarity Score 0.77
HY-50736DUB-IN-1 -
Similarity Score 0.71
HY-32247DCAF -
Similarity Score 0.64
HY-101666RHBX 41108 (Standard) -
Similarity Score 0.60
HY-114315NQO1 substrate -
Similarity Score 0.55
HY-100233AIQ-1S -
Similarity Score 0.52
HY-100233IQ-1S free acid -
Similarity Score 0.50
HY-107600RIQ-3 (Standard) -
Similarity Score 0.49
HY-144115A1AR antagonist 1 -
Explore the MedChemAI to find more analogs
