928161-33-5
Chemical Structure
AX8819
- CAS No.: 928161-33-5
- Formula:C11H21N3O
- Molecular Weight:211.30
InChIKey: NSAIVORPWCLAMZ-KXUCPTDWSA-N
SMILES: NCC[C@H](N)C(N1[C@@]2([H])[C@@](CCC2)([H])CC1)=O
Biological Activity: AX8819 is a selective dipeptidyl peptidase II (DPP II) inhibitor with an IC50 of 0.88 nM. AX8819 induces caspase-dependent apoptosis. AX8819 exhibits low non-specific toxicity toward proliferating T cells. AX8819 can be used for the research of B cell chronic lymphocytic leukemia[1].
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AX8819 | AX8819 is a selective dipeptidyl peptidase II (DPP II) inhibitor with an IC50 of 0.88 nM. AX8819 induces caspase-dependent apoptosis. AX8819 exhibits low non-specific toxicity toward proliferating T cells. AX8819 can be used for the research of B cell chronic lymphocytic leukemia. | |||||||||||||||||||||
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Keywords