936095-50-0
Chemical Structure
UBP316
Synonym(s): ACET
- CAS. Nr.: 936095-50-0
- Formula:C20H19N3O6S
- Molecular Weight:429.45
IUPAC Name: (S)-3-((3-(2-amino-2-carboxyethyl)-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)methyl)-5-phenylthiophene-2-carboxylic acid
InChIKey: LCZDCKMQSBGXAH-AWEZNQCLSA-N
SMILES: OC(C(SC(C1=CC=CC=C1)=C2)=C2CN3C(N(C=C(C)C3=O)C[C@H](N)C(O)=O)=O)=O
Biological Activity: UBP316 (ACET) is a highly potent and selective kainate receptor GluK1 (GluR5) antagonist, with a Kb value of 1.4 nM. UBP316 is effective at blocking the depression of both field excitatory postsynaptic potentials (fEPSPs) and monosynaptically-evoked GABAergic transmission induced by ATPA, a GluK1 selective agonist[1].
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UBP316 | 99.06% | UBP316 (ACET) is a highly potent and selective kainate receptor GluK1 (GluR5) antagonist, with a Kb value of 1.4 nM. UBP316 is effective at blocking the depression of both field excitatory postsynaptic potentials (fEPSPs) and monosynaptically-evoked GABAergic transmission induced by ATPA, a GluK1 selective agonist. | ||||||||||||||||||||
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