937263-43-9
937263-43-9
Chemical Structure
Tucatinib
Synonym(s): Irbinitinib; ARRY-380; ONT-380
- CAS No.: 937263-43-9
- Formula:C26H24N8O2
- Molecular Weight:480.52
IUPAC Name: N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine
InChIKey: SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES: CC1=CC(NC2=C3C=C(NC4=NC(C)(C)CO4)C=CC3=NC=N2)=CC=C1OC5=CC6=NC=NN6C=C5
Biological Activity: Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tucatinib | 99.48% | Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. | ||||||||||||||||||||
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Tucatinib (Standard) | ≥98% | Tucatinib (Standard) is the analytical standard of Tucatinib. This product is intended for research and analytical applications. Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. | ||||||||||||||||||||
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Tucatinib-d6 | Tucatinib-d6 (Irbinitinib-d6) is deuterium labeled Tucatinib. Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. | |||||||||||||||||||||
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