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Referencia número: HY-16069R

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Tucatinib (Standard)

Name: Tucatinib (Standard)
Brand: MedChemExpress
SKU: HY-16069R
Price: 125.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Irbinitinib (Standard); ARRY-380 (Standard); ONT-380 (Standard))

Tucatinib (Standard) is the analytical standard of Tucatinib. This product is intended for research and analytical applications. Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza : 98%
No. CAS: 937263-43-9
Fòrmula: C₂₆H₂₄N₈O₂
Peso molecular:480.52

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tucatinib (Standard) Chemical Structure

No. CAS: 937263-43-9

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Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Product Information
- Information
- Aplicación
Chemical Information
Pureza y Documentación
Calculators
Help & FAQs
Classifications
Bioz

Product Information

Information

Aplicación

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

No. CAS 937263-43-9
Peso molecular 480.52
Fòrmula C₂₆H₂₄N₈O₂
SMILES

CC1=CC(NC2=C3C=C(NC4=NC(C)(C)CO4)C=CC3=NC=N2)=CC=C1OC5=CC6=NC=NN6C=C5
Synonyms

Irbinitinib (Standard); ARRY-380 (Standard); ONT-380 (Standard)
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Referencias

[1]. Moulder-Thompson S, et al. Phase 1 Study of ONT-380, a HER2 Inhibitor, in Patients with HER2⁺ Advanced Solid Tumors, with an Expansion Cohort in HER2+ Metastatic Breast Cancer (MBC). Clin Cancer Res. 2017 Jan 4. pii: clincanres.1496.2016. [Content Brief]

[2]. Abstract: In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 852. doi:1538-7445.AM2012-852

[3]. P. Lee, et al. In Vivo Activity of ARRY-380, a Potent, Small Molecule Inhibitor of ErbB2 in Combination with RP-56976. Cancer Research

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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