943540-74-7
943540-74-7
Chemical Structure
JNJ-38877618
- CAS. Nr.: 943540-74-7
- Formula:C20H12F2N6
- Molecular Weight:374.35
IUPAC Name: 6-(difluoro(6-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
InChIKey: KOAWAWHSMVKCON-UHFFFAOYSA-N
SMILES: FC(C1=CC=C2N=CC=CC2=C1)(F)C3=NN=C4C=CC(C5=CC=NC=C5)=NN43
Biological Activity: JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively.
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JNJ-38877618 | 98.85% | JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively. | ||||||||||||||||||||
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JNJ-38877618 (Standard) | ≥98% | JNJ-38877618 (Standard) is the analytical standard of JNJ-38877618 (HY-111050). This product is intended for research and analytical applications. JNJ-38877618 is a potent, highly selective, orally bioavailable Met Kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively. | ||||||||||||||||||||
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