943540-74-7
943540-74-7
Chemical Structure
JNJ-38877618
- CAS No.: 943540-74-7
- Formula:C20H12F2N6
- Molecular Weight:374.35
IUPAC Name: 6-(difluoro(6-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
InChIKey: KOAWAWHSMVKCON-UHFFFAOYSA-N
SMILES: FC(C1=CC=C2N=CC=CC2=C1)(F)C3=NN=C4C=CC(C5=CC=NC=C5)=NN43
Biological Activity: JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JNJ-38877618 | 98.85% | JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively. | ||||||||||||||||||||
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JNJ-38877618 (Standard) | ≥98% | JNJ-38877618 (Standard) is the analytical standard of JNJ-38877618 (HY-111050). This product is intended for research and analytical applications. JNJ-38877618 is a potent, highly selective, orally bioavailable Met Kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-50683JNJ-38877605 -
Similarity Score 0.72
HY-50683SJNJ-38877605-d1 -
Similarity Score 0.61
HY-14510PF 04254644 -
Similarity Score 0.59
HY-157302c-Met-IN-21 -
Similarity Score 0.57
HY-12019SGX-523 -
Similarity Score 0.56
HY-15456NVP-BVU972 -
Similarity Score 0.55
HY-153896LMTK3-IN-1 -
Similarity Score 0.55
HY-125017Bozitinib -
Similarity Score 0.54
HY-12035AMG-208 -
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