950386-41-1
950386-41-1
Chemical Structure
MAC-0547630
- CAS No.: 950386-41-1
- Formula:C19H21FN4
- Molecular Weight:324.40
IUPAC Name: 7-(azepan-1-yl)-3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine
InChIKey: MWBKFQJPGCZDRF-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=C(N=C(C)C=C3N4CCCCCC4)N3N=C2)C=C1
Biological Activity: MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppSBS and UppSBA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL)[1].
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MAC-0547630 | MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppSBS and UppSBA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL). | |||||||||||||||||||||
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References
Keywords
