950665-12-0
950665-12-0
Chemical Structure
FLDP-5
- CAS No.: 950665-12-0
- Formula:C21H21NO5
- Molecular Weight:367.40
IUPAC Name: 3,5-bis((E)-4-hydroxy-3-methoxybenzylidene)piperidin-4-one
InChIKey: QKBRHSFMRAGHMJ-BGPOSVGRSA-N
SMILES: O=C1/C(CNC/C1=C\C2=CC=C(O)C(OC)=C2)=C/C3=CC=C(O)C(OC)=C3
Biological Activity: FLDP-5 is a blood-brain barrier (BBB) penetrant curcuminoid analogues. FLDP-5 can induce production of ROS (Reactive Oxygen Species), DNA damage and cell cycle S phase arrest. FLDP-5 exhibits highly potent tumour-suppressive effects with anti-proliferative and anti-migratory activities on LN-18 cells[1].
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FLDP-5 | FLDP-5 is a blood-brain barrier (BBB) penetrant curcuminoid analogues. FLDP-5 can induce production of ROS (Reactive Oxygen Species), DNA damage and cell cycle S phase arrest. FLDP-5 exhibits highly potent tumour-suppressive effects with anti-proliferative and anti-migratory activities on LN-18 cells. | |||||||||||||||||||||
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References
Keywords
