99-45-6
99-45-6
Chemical Structure
Adrenalone
- CAS No.: 99-45-6
- Formula:C9H11NO3
- Molecular Weight:181.19
IUPAC Name: 1-(3,4-dihydroxyphenyl)-2-(methylamino)ethan-1-one
InChIKey: PZMVOUYYNKPMSI-UHFFFAOYSA-N
SMILES: CNCC(C1=CC=C(O)C(O)=C1)=O
Biological Activity: Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM[1][2].
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Adrenalone | 95.09% | Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM. | ||||||||||||||||||||
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References
- [1]. M GOLDSTEIN,et al. Inhibition of dopamine beta oxidase by adrenalone. Nature.1961 Dec 16;192:1081. [Content Brief]
- [2]. Avner Schlessinger, et al. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15810-5. [Content Brief]
Keywords
