99899-45-3
Chemical Structure
SM-2470
- CAS No.: 99899-45-3
- Formula:C23H30ClN5O3
- Molecular Weight:459.97
IUPAC Name: (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(bicyclo[2.2.2]oct-5-en-2-yl)methanone hydrochloride
InChIKey: IHBVUYHTCGEQHD-UHFFFAOYSA-N
SMILES: NC1=NC(N(CC2)CCN2C(C3C(C=C4)CCC4C3)=O)=NC(C=C5OC)=C1C=C5OC.Cl
Biological Activity: SM-2470 is a potent α1-adrenoceptor antagonist, has sympathetic nerve activity in anesthetized rats[1]. SM-2470 is an antihypertensive agent. SM-2470 exhibits hypocholesterolaemic effect by the inhibition of cholesterol absorption related to the reduction of cholesterol solubilization[2].
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SM-2470 | SM-2470 is a potent α1-adrenoceptor antagonist, has sympathetic nerve activity in anesthetized rats. SM-2470 is an antihypertensive agent. SM-2470 exhibits hypocholesterolaemic effect by the inhibition of cholesterol absorption related to the reduction of cholesterol solubilization. | |||||||||||||||||||||
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Keywords