CaSR antagonist-1
CaSR antagonist-1 is a calcium sensing receptor (CaSR) antagonist with an IC50 value of 50 nM. CaSR antagonist-1 can be used for the research of disorders associated with abnormal bone or mineral homeostasis such as osteoporosis.
For research use only. We do not sell to patients.
- CAS No.: 1219811-83-2
- Formula: C29H24FN3O2S
- Molecular Weight:497.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50:50 nM (CaSR)[1].EC50:＞50 μM (hPXR Gene reporter assay)[1].
Chemical Information
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CAS No. 1219811-83-2
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Molecular Weight 497.58
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Formula C29H24FN3O2S
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SMILES
O=C1C(C2=CC(C3=CC=CC=N3)=C(C)S2)=C(C)N=C(N1CCC4=CC=CC=C4)C5=C(O)C(F)=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CaSR antagonist-1 Related Classifications
HY-153258 Related Classifications
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