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Art. -Nr.: HY-161418

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1-NBX

1-NBX is a potent and selective A₁R ligand. 1-NBX exhibits significantly improved A₁R affinity with with a K_i of 2.6 nM and lower affinity for the A₂A receptor with a K_i of 164 nM.

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Formel: C₁₈H₂₅FN₄O₂
Molecular Weight:348.42

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

1-NBX Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

1-NBX is a potent and selective A₁R ligand. 1-NBX exhibits significantly improved A₁R affinity with with a K_i of 2.6 nM and lower affinity for the A₂A receptor with a K_i of 164 nM^[1].

Alle Adenosine Receptor Isoform-spezifische Produkte anzeigen :

Chemical Information

Molecular Weight 348.42
Formel C₁₈H₂₅FN₄O₂
SMILES

O=C1C2=C(N=C([C@]34CC[C@@H](C4)CC3)N2)N(CCCF)C(N1CCC)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Swen Humpert, et al. 8-Bicycloalkyl-CPFPX derivatives as potent and selective tools for in vivo imaging of the A1 adenosine receptor. Eur J Med Chem. 2024 Apr 6:271:116380. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Chemical Information
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1-NBX

Alle Adenosine Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

1-NBX Related Classifications

HY-161418 Related Classifications

Bioz

Keywords

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