3-Picolylamine-d2
3-Picolylamine-d2 (Picolamine-d2) is the deuterium labeled 3-Picolylamine (HY-Y0047). 3-Picolylamine is a primary amine compound containing a pyridine ring structure. 3-Picolylamine inhibits histaminase (diamine oxidase) activity in pig kidneys. 3-Picolylamine significantly enhances the contractile response of isolated guinea pig ileum to Histamine (HY-B1204). 3-Picolylamine can be used to study histamine-related physiological mechanisms or allergic diseases (such as histamine-mediated inflammatory responses).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C6H6D2N2
- Molecular Weight:110.15
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 3731-52-0
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Molecular Weight 110.15
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Formel C6H6D2N2
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SMILES
NC([2H])(C1=CC=CN=C1)[2H]
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Synonyms
Picolamine-d2; 3-Pyridinemethanamine-d2; Pyridin-3-ylmethanamine-d2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Park Y, et al. Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01006-19. [Content Brief]
[2]. BLASCHKO H, et al. Potentiation of the response to histamine by picolylamines. Br J Pharmacol Chemother. 1962 Dec;19(3):544-51. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
3-Picolylamine-d2 Related Classifications
HY-Y0047S Related Classifications
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