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Abetimus

(Synonyms: LJP 394 free base)

Abetimus (LJP 394 free base) is an immunosuppressant consisting of four double-stranded DNA (dsDNA) oligonucleotides. Abetimus is capable of crosslinking anti-dsDNA antibodies on the surface of B cells, and decreases anti-dsDNA antibodies levels. Abetimus has the potential for research of systemic lupus erythematosus.

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  • CAS. Nr.: 167362-48-3
  • Formel: C1632H2100N610O97P156S4
  • Molecular Weight:50742.05
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Abetimus Chemical Structure
    Abetimus Chemical Structure
CAS. Nr.: 167362-48-3
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  • Abetimus Chemical Structure
    Abetimus Chemical Structure DNA, d(C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A), 5′-ester with 1,2-ethanediylbis(oxy-2,1-ethanediyl)bis[2-(21,21-dihydroxy-21-oxido-4,11-dioxo-20-oxa-13-thia-3,10-diaza-21-phosphaheneicos-1-yl)-23,23-dihydroxy-23-oxido-6,13-dioxo-22-oxa-15-thia-2,5,12-triaza-23-phosphatricosanoate] (4:1), complex with DNA d(T-G-T-G-T-G-T-G-T-G-T-G-T-G-T-G-T-G-T-G) (1:1)
    1/16
  • DNA, d(C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A-C-A), 5′-ester with 1,2-ethanediylbis(oxy-2,1-ethanediyl)bis[2-(21,21-dihydroxy-21-oxido-4,11-dioxo-20-oxa-13-thia-3,10-diaza-21-phosphaheneicos-1-yl)-23,23-dihydroxy-23-oxido-6,13-dioxo-22-oxa-15-thia-2,5,12-triaza-23-phosphatricosanoate] (4:1), complex with DNA d(T-G-T-G-T-G-T-G-T-G-T-G-T-G-T-G-T-G-T-G) (1:1)