country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-183550

Copy Link Print Information

Antitubercular agent-58

Antitubercular agent-58 is an antitubercular agent with an IC₅₀ of 51 nM against Mycobacterium tuberculosis H37Rv. Antitubercular agent-58 can be used for the research of tuberculosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₂H₂₂FN₃O₃
Molecular Weight:395.43

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antitubercular agent-58 Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Antitubercular agent-58 is an antitubercular agent with an IC₅₀ of 51 nM against Mycobacterium tuberculosis H37Rv. Antitubercular agent-58 can be used for the research of tuberculosis^[1].

In Vitro

Antitubercular agent-58 (Compound 20j) potently inhibits the growth of Mycobacterium tuberculosis H37Rv whole cells with an IC₅₀ of 51 nM^[1].
Antitubercular agent-58 shows high metabolic clearance in rat hepatocytes and moderate metabolic clearance in human liver microsomes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 395.43
Formel C₂₂H₂₂FN₃O₃
SMILES

O=C1C(C(C2=CC=C(N3C[C@@H](C)O[C@@H](C)C3)C=C2)=C1NCC4=NC(F)=CC=C4)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Mosallam N, et al. Second-Generation Anti-Tubercular Squaramides Targeting Complex V of the Respiratory Chain of Mycobacterium tuberculosis Displaying Enhanced Metabolic Stability. J Med Chem. 2026 May 14;69(9):10213-10239. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen