Argatroban-d3
Argatroban-d3 is the deuterium labeled Argatroban. Argatroban (MD-805) is a direct, selective thrombin inhibitor.
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- CAS. Nr.: 1356847-56-7
- Formel: C23H33D3N6O5S
- Molecular Weight:511.65
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Ticagrelor-d7Stable Isotope -
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Octacosanoic acid (Standard)Reference Standard -
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1356847-56-7
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Unlabeled CAS 74863-84-6
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Molecular Weight 511.65
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Formel C23H33D3N6O5S
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SMILES
O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(CC(CN3)C([2H])([2H])[2H])=CC=C2)=O
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Synonyms
MD-805-d3; MCI-9038-d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9. [Content Brief]
[3]. Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Argatroban-d3 Related Classifications
HY-B0375S Related Classifications
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