199331-35-6
199331-35-6
Chemical Structure
Dehydroglyasperin C
- CAS. Nr.: 199331-35-6
- Formula:C21H22O5
- Molecular Weight:354.40
IUPAC Name: 4-(7-hydroxy-5-methoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-3-yl)benzene-1,3-diol
InChIKey: UACNRZUVCUEUPY-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=CC3=C(OC)C(C/C=C(C)\C)=C(O)C=C3OC2)C(O)=C1
Biological Activity: Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Dehydroglyasperin C | 99.12% | Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.88
HY-N3716Dehydroglyasperin D -
Similarity Score 0.77
HY-W925682Bidwillol A -
Similarity Score 0.70
HY-N3199Neorauflavene -
Similarity Score 0.66
HY-N9919Glyasperin C -
Similarity Score 0.63
HY-208247Haginin D -
Similarity Score 0.61
HY-N8254Haginin A -
Similarity Score 0.60
HY-N7969Odoriflavene -
Similarity Score 0.60
HY-1421013,4-Didehydroglabridin -
Similarity Score 0.59
HY-N6975Glyasperin D -
Explore the MedChemAI to find more analogs
References
- [1]. Hyo Jung Kim, et al. Dehydroglyasperin C, a component of liquorice, attenuates proliferation and migration induced by platelet-derived growth factor in human arterial smooth muscle cells. Br J Nutr. 2013 Aug 28;110(3):391-400. [Content Brief]
- [2]. Ji Hoon Lee, et al. Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K. Mol Carcinog. 2016 May;55(5):552-62. [Content Brief]
- [3]. Ji Yeon Seo, et al. Dehydroglyasperin C isolated from licorice caused Nrf2-mediated induction of detoxifying enzymes. J Agric Food Chem. 2010 Feb 10;58(3):1603-8. [Content Brief]
