85532-75-8
85532-75-8
Chemical Structure
PK 11195
Synonym(s): RP 52028
- CAS. Nr.: 85532-75-8
- Formula:C21H21ClN2O
- Molecular Weight:352.86
IUPAC Name: N-(sec-butyl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide
InChIKey: RAVIZVQZGXBOQO-UHFFFAOYSA-N
SMILES: O=C(N(C(CC)C)C)C1=CC2=CC=CC=C2C(C3=CC=CC=C3Cl)=N1
Biological Activity: PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.
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PK 11195 | 99.91% | PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively. | ||||||||||||||||||||
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PK 11195 (Standard) | ≥98% | PK 11195 (Standard) is the analytical standard of PK 11195. This product is intended for research and analytical applications. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-118096AHN 070 -
Similarity Score 0.70
HY-141804ER176 -
Similarity Score 0.70
HY-100346PK14105 -
Similarity Score 0.53
HY-114994MS437 -
Similarity Score 0.51
HY-W488313R6-Chloro-4-(2-chlorophenyl)quinazoline-2-carbaldehyde (Standard) -
Similarity Score 0.50
HY-176975DRP1 Allosteric-IN-3 -
Similarity Score 0.50
HY-176974DRP1 Allosteric-IN-2 -
Similarity Score 0.49
HY-W777622ent-Calindol amide-13C -
Similarity Score 0.49
HY-W087946Chlorfenazole -
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