EGFR-IN-30
EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, <1 nM for EGFR (WT), EGFR (L858R/T790M/C797S), respectively. EGFR-IN-30 has potential for cell proliferative diseases, such as cancer research.
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- CAS. Nr.: 2726463-68-7
- Formel: C28H33BrN7O2P
- Molecular Weight:610.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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EGFR (WT) 1-10 nM (IC50) |
EGFR (L858R/T790M/C797S) <1 nM (IC50) |
EGFR-IN-30 (compound 27) inhibits A431 cell (IC50=100-1000 nM),Ba/F3_L858R/T790M/C797S cell (IC50<10 nM), Ba/F3_Del19/T790M/C797S cell (IC50<10 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2726463-68-7
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Molecular Weight 610.49
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Formel C28H33BrN7O2P
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SMILES
O=P(C)(C)C1=C(NC2=NC(NC3=C(OC)C=C4N(C(C)C)CCC5=C(C=NN5C)C4=C3)=NC=C2Br)C=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EGFR-IN-30 Related Classifications
HY-144044 Related Classifications
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