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Art. -Nr.: HY-105762

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Etamiphyllin

Name: Etamiphyllin
Brand: MedChemExpress
SKU: HY-105762
Price: 130.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Etamiphylline)

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Etamiphyllin (Etamiphylline) is a respiratory and cardiac stimulant. Etamiphyllin camsylate relaxes bronchial and bronchiolar smooth muscle to open airways, and increases cardiac output without elevating heart rate. The level of Etamiphyllin camsylate decreases in mice with ulcerative colitis, and it is positively correlated with *Bifidobacterium* and *Faecalibacterium*. Etamiphyllin camsylate can be applied to research related to chronic obstructive pulmonary disease, respiratory failure and ulcerative colitis.

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Reinheit : 99.33%
CAS. Nr.: 314-35-2
Formel: C₁₃H₂₁N₅O₂
Molecular Weight:279.34

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Etamiphyllin Chemical Structure

CAS. Nr.: 314-35-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vivo

Etamiphyllin (2.8 mg/kg; i.v.; single dose) administered intravenously to healthy male Thoroughbred horses results in detection of the parent drug and three metabolites in plasma and urine up to 32 hours post-administration, with N-desethyletamiphylline as the primary metabolite and N-desethyl-N-desmethyletamiphylline detected only in urine^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Thoroughbred (male, ages 6 and 16, body weights 498 and 537 kg)^[2]
Dosage:

2.8 mg/kg
Administration:

i.v.; single dose
Result:

Detected in plasma and urine samples, with a characteristic m/z 207 fragment ion from loss of N,N-diethylamine.
Detected the main metabolite, N-desethyletamiphylline (molecular weight 251), in plasma and urine up to 32 hours post-administration, with a protonated molecular ion ([M+H]+) at m/z 252.1455 and product ions at m/z 207.0879 and m/z 163.0979.
Detected two isomers of N1/N3-desmethyletamiphylline (molecular weight 265) as minor metabolites in plasma and urine, with [M+H]+ ions at m/z 266.1613 and m/z 266.1615, and common product ion m/z 193.0721/193.0723 from loss of N,N-diethylamine.
Detected N-desethyl-N-desmethyletamiphylline (molecular weight 238) as a minor metabolite in urine, with [M+H]+ ion at m/z 238.1300 and product ion m/z 193.0722 from loss of N-ethylamine.

Related Protocols :

Chemical Information

CAS. Nr. 314-35-2
Appearance Solid
Molecular Weight 279.34
Formel C₁₃H₂₁N₅O₂
Color White to off-white
SMILES

O=C1C2=C(N(C)C(N1C)=O)N=CN2CCN(CC)CC
Synonyms

Etamiphylline
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Song Y, et al. Ameliorative effects and mechanism of Panax notoginseng extract on ulcerative colitis mice based on a multi-omics strategy[J]. Frontiers in Immunology, 2025, 16: 1727993.

[2]. Wieder M E, et al. Identification of etamiphylline and metabolites in equine plasma and urine by accurate mass and liquid chromatography/tandem mass spectrometry[J]. Drug Testing and Analysis, 2010, 2(6): 271-277. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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