Agrp - agouti related neuropeptide Gene

Also Known as Art; Agrt

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11604

Summary

This gene encodes a protein that regulates feeding behavior and plays a key role in the control of body weight. The encoded protein acts as an antagonist of Melanocortin Receptor signaling. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2012]

Agrp Products (2)

mRNA Protein Name
NM_001271806.1 NP_001258735.1 agouti-related protein precursor
NM_007427.3 NP_031453.1 agouti-related protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables neuropeptide hormone activity IDA
IDA: Inferred from direct assay
9311920 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within adult feeding behavior IDA
IDA: Inferred from direct assay
17873059 MGI
acts upstream of or within neuropeptide signaling pathway IDA
IDA: Inferred from direct assay
9311920 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

agouti-related protein

  • orexigenic neuropeptide

Recombinant Agrp Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P75523 AGRP Protein, Mouse (HEK293, His) P56473 (V21-T131) ≥ 80%, as determined by reducing SDS-PAGE.
HY-P75524 AGRP Protein, Mouse (50a.a, HEK293, Fc) P56473/NP_031453.1 (S82-T131) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P75525 AGRP Protein, Mouse (HEK293, Fc) P56473 (V21-T131) ≥ 85%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-116797 MS15203 99.40% Unkown
HY-P3561A Agouti-related Protein (AGRP) (83-132) Amide (human) TFA Inhibitor 98.30% Unkown
HY-P3561 Agouti-related Protein (AGRP) (83-132) Amide (human) Antagonist / Unkown
HY-P3924 Agouti-Related Protein (54-82) (human) Inhibitor / Unkown
HY-RS00465 AGRP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17733 Agrp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24198 Agrp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agrp NCBI NCBI:181