Tyro3 - TYRO3 protein tyrosine kinase Gene

Also Known as Brt

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25232

Summary

Enables phosphatidylinositol 3-kinase binding activity. Involved in protein phosphorylation. Located in endoplasmic reticulum membrane and nuclear envelope. Orthologous to human Tyro3 (Tyro3 protein tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Tyro3 Products (1)

mRNA Protein Name
NM_017092.1 NP_058788.1 tyrosine-protein kinase receptor TYRO3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables phosphatidylinositol 3-kinase binding IPI
IPI: Inferred from physical interaction
10627473 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
10627473 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
9175267 RGD
located in nuclear envelope IDA
IDA: Inferred from direct assay
9175267 RGD
located in nucleus IDA
IDA: Inferred from direct assay
9175267 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase receptor TYRO3

  • Bruton agammaglobulinemia tyrosine kinase

  • TYRO3 protein tyrosine kinase 3

  • tyrosine-protein kinase SKY

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-12076 BMS 777607 Inhibitor 99.36% Phase 2
HY-114358 Tamnorzatinib Inhibitor 98.59% Phase 2
HY-147218 PF-07265807 Inhibitor 95.18% Phase 1

Pre-clinical Phase

Bioactive Molecules (9)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-12494 LDC1267 Inhibitor 99.64% Unkown
HY-117596 UNC569 Inhibitor 99.92% Unkown
HY-132200 UNC5293 Inhibitor 99.93% Unkown
HY-173268 UNC9426 Inhibitor 99.51% Unkown
HY-117548 UNC1062 Inhibitor 98.92% Unkown
HY-124502 UNC4203 Inhibitor 99.80% Unkown
HY-162085 Axl-IN-17 Inhibitor / Unkown
HY-173400 UNC8212 Inhibitor / Unkown
HY-115778 UNC3133 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tyro3 NCBI NCBI:7301
Macaca fascicularis Tyro3 NCBI NCBI:102135978
Mus musculus Tyro3 NCBI NCBI:22174