Meltf - melanotransferrin Gene

Also Known as MTf; Mfi2; CD228

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30060

Summary

Predicted to enable iron ion binding activity. Predicted to be involved in several processes, including negative regulation of substrate adhesion-dependent cell spreading; positive regulation of extracellular matrix disassembly; and positive regulation of plasminogen activation. Predicted to act upstream of or within ion transport and iron ion homeostasis. Predicted to be located in cell surface. Predicted to be anchored component of plasma membrane. Predicted to be active in endosome; extracellular space; and plasma membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; integumental system; and sensory organ. Orthologous to human MELTF (melanotransferrin). [provided by Alliance of Genome Resources, Apr 2022]

Meltf Products (1)

mRNA Protein Name
NM_013900.2 NP_038928.1 melanotransferrin precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
NOT acts upstream of or within intracellular iron ion homeostasis IMP
IMP: Inferred from mutant phenotype
16291590 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

melanotransferrin

  • antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

  • membrane-bound transferrin-like protein p97

Recombinant Meltf Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P76495 Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) Q9R0R1 (V20-Q708) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P76496 Melanotransferrin/CD228 Protein, Mouse (HEK293, His) Q9R0R1 (V20-Q708) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08331 MELTF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20054 Meltf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26558 Meltf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Meltf NCBI NCBI:4241