Huperzine C
Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease.
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- CAS. Nr.: 163089-71-2
- Formel: C15H18N2O
- Molecular Weight:242.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 0.6 μM (AChE)[2]
Chemical Information
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CAS. Nr. 163089-71-2
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Molecular Weight 242.32
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Formel C15H18N2O
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SMILES
O=C1C=CC([C@@]([C@@H]2C=C)(N)CC(C)=C[C@@]2([H])C3)=C3N1
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
[1]. Fangfang Jiang, et al. Lycopodium alkaloids from Huperzia serrate. Fitoterapia.. 2019 Sep;137:104277. [Content Brief]
[2]. Dong-Bo Zhang, et al. Lycodine-Type Alkaloids from Lycopodiastrum casuarinoides and Their Acetylcholinesterase Inhibitory Activity. Molecules. 2014 Jul; 19(7): 9999–10010. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Huperzine C Related Classifications
HY-122957 Related Classifications
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