Malabaric acid
Malabaric acid is a cyclooxygenase inhibitor that inhibits COX-1 (IC50 = 11.5 µM) and COX-2 (IC50 = 46.9 µM). Malabaric acid inhibits lipid peroxidation and can be used in antioxidant research.
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- CAS. Nr.: 67910-87-6
- Formel: C20H30O2
- Molecular Weight:302.45
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
COX-1 11.5 μM (IC50) |
COX-2 46.9 μM (IC50) |
In Vitro
Malabaric acid (10.3-164.8 µM; 21 min) inhibits lipid peroxidation in a liposome-based LPO assay, with an IC50 of 100.3 µM[1].
Malabaric acid (41.2-329.6 µM; 24 h) exhibits moderate MTT-reducing antioxidant activity in a cell-free MTT assay, with an IC50 of 192 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 67910-87-6
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Molecular Weight 302.45
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Formel C20H30O2
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SMILES
O=C(/C1=C\CC/C(C)=C/C[C@H](C(C)=C)CC/C(C)=C/CC1)O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Malabaric acid Related Classifications
HY-N22072 Related Classifications
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