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Art. -Nr.: HY-N3215

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Nagilactone C

Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines.

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CAS. Nr.: 24338-53-2
Formel: C₁₉H₂₂O₇
Molecular Weight:362.37

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Nagilactone C Chemical Structure

CAS. Nr.: 24338-53-2

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
AGS	IC₅₀	2.3 μM Compound: 7j	Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay Cytotoxicity against human AGS cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
HeLa	IC₅₀	3.3 μM Compound: 7j	Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay Cytotoxicity against human HeLa cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
HepG2	IC₅₀	14 μM Compound: 7j	Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
MDA-MB-231	IC₅₀	5 μM Compound: 7j	Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]
P388	IC₅₀	0.33 μg/mL Compound: 1	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 1800635]
PANC-1	IC₅₀	>40 μM Compound: 7j	Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay Cytotoxicity against human Panc-1 cells incubated for 48 hrs by MTT assay	[PMID: 33289552]

Chemical Information

CAS. Nr. 24338-53-2
Molecular Weight 362.37
Formel C₁₉H₂₂O₇
SMILES

C[C@@]1(C2=C3)[C@]4([H])[C@]([C@@H](O)[C@@H]5[C@H]1O5)(C(O[C@]4([H])[C@H](O)C2=C(C(C)C)OC3=O)=O)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. K Shrestha, et al. An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius. Phytomedicine. 2001 Nov;8(6):489-91. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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