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Art. -Nr.: HY-187460

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RIPK1-IN-43

RIPK1-IN-43 is a triazolopyridine compound and also a RIPK1 inhibitor. RIPK1-IN-43 can be used in the research of diseases associated with abnormal RIPK1, such as multiple sclerosis, Parkinson's disease, non-alcoholic steatohepatitis, etc.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₂H₁₇F₄N₉
Molecular Weight:483.42

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

RIPK1-IN-43 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

RIPK1

Alle RIP kinase Isoform-spezifische Produkte anzeigen :

In Vitro

RIPK1-IN-43 (Example 2) exhibits an IC₅₀ of 4.2 nM in the high-content assay of MLKL phosphorylation in HT29‑L23 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 483.42
Formel C₂₂H₁₇F₄N₉
SMILES

CC(F)(F)C(C1=CC(F)=CC(F)=C1)N(N=C2)N=C2C3=NC(C4=C(C)C5=NC(N)=NN5C=C4)=CN=C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Shi J L, et al. Triazolopyridinyl compounds as kinase inhibitors. WO2026155973A1, WIPO, 2026.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
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RIPK1-IN-43

Alle RIP kinase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

RIPK1-IN-43 Related Classifications

HY-187460 Related Classifications

Bioz

Keywords

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