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Art. -Nr.: HY-163825

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RNB-61

Name: RNB-61
Brand: MedChemExpress
SKU: HY-163825
Availability: PreOrder

RNB-61 is an oral active agonist of cannabinoid CB2 receptor (CB2R), with the K_i ranging from 0.13 nM to 1.81 nM. RNB-61 has nephroprotective and/or antifibrotic effects. RNB-61 has negligible penetration into the brain.

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Formel: C₂₅H₃₄F₃N₃O₃

Molecular Weight:481.55

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

RNB-61 Chemical Structure

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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Data Download

Data Sheet (271 KB)

Handling Instructions (2659 KB)

Other Forms of RNB-61:

(E)-RNB-61
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Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Help & FAQs

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Alle Cannabinoid Receptor Isoform-spezifische Produkte anzeigen
More

CB1

CB2

Biologische Aktivität

Beschreibung

Chemical Information

Reinheit & Dokumentation

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Calculators

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Classifications

Bioz

Biologische Aktivität

Beschreibung

RNB-61 is an oral active agonist of cannabinoid CB2 receptor (CB2R), with the K_i ranging from 0.13 nM to 1.81 nM. RNB-61 has nephroprotective and/or antifibrotic effects. RNB-61 has negligible penetration into the brain^[1].

Alle Cannabinoid Receptor Isoform-spezifische Produkte anzeigen :

CB1

CB2

Chemical Information

Molecular Weight 481.55

Formel C₂₅H₃₄F₃N₃O₃

SMILES

CN1C(C(C)(C)C)=C/C(N1CC2CCC2)=N\C(C3=C(C=CC(C(F)(F)F)=C3)OCC(C)(O)C)=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Andrea Chicca, et al. A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Konzentration Konzentration

×
Volumen Volumen

×
Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

×

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

=

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

×

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

RNB-61 Related Classifications

HY-163825 Related Classifications

GPCR/G Protein Neuronal Signaling

Cannabinoid Receptor

Disease Areas

Neurological, Eye or Ear Disease Inflammation or Immune System Disease

Neurological Disease Inflammation/Immunology

Bioz

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Keywords

RNB-61
RNB61
RNB 61
Cannabinoid Receptor
AKI/CKI models
pharmacokinetic (PK) properties
Inhibitor
inhibitor
inhibit

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