(S)-BMS-378806
(S)-BMS-378806 ((S)-BMS-806) is an orally bioavailable HIV-1 inhibitor with activity against gp120-CD4 interactions. (S)-BMS-378806 exhibits micromolar inhibition of HIV-1 gp120-CD4 binding. The design and synthesis of (S)-BMS-378806 was based on a comprehensive study of protein-ligand interactions, which guided the identification and design of novel symmetrical N,N'-disubstituted aminoureas and thioureas. (S)-BMS-378806, synthesized in aqueous media using microwave irradiation, was validated for its inhibitory activity in HIV-1 gp120-CD4 capture ELISA.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 357263-14-0
- Formel: C22H22N4O4
- Molecular Weight:406.43
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Chemical Information
-
CAS. Nr. 357263-14-0
-
Molecular Weight 406.43
-
Formel C22H22N4O4
-
SMILES
C[C@@H]1N(CCN(C1)C(C2=CC=CC=C2)=O)C(C(C3=CNC4=NC=CC(OC)=C43)=O)=O
-
Synonyms
(S)-BMS-806
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(S)-BMS-378806 Related Classifications
HY-119202 Related Classifications
Powered by Bioz