Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
129 Results for "
Configuration
" in MedChemExpress (MCE) Product Catalog:
Products (129)
129 Results for "Configuration" in MCE Product Catalog:
11
11 Publications Verification
(E/Z)-Mirin is a mixture of (E)-Mirin and Mirin ((Z)-Mirin) (HY-19959) configurations. Among them, Mirin is an inhibitor of MRN (Mre11-Rad50-Nbs1). Mirin prevents MRN-dependent ATM activation without affecting ATM protein kinase activity .
7
7 Cited Publications
Art. -Nr.: HY-W010347
CAS. Nr.: 6027-13-0
Category:
Human Gut Microbiota Metabolites Microorganisms Anti-aging Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Art. -Nr.: HY-W018035
CAS. Nr.: 473-81-4
Synonyms: Glyceric Acid (20% in Water,ca.2 mol/L)
Category:
Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
1
Target:
1
1 Cited Publications
Art. -Nr.: HY-W653733
CAS. Nr.: 331665-12-4
1
Target:
Forschungsgebiete:
Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice .
1
1 Cited Publications
Art. -Nr.: HY-128838A
Reinheit: 98.18%
Target:
Forschungsgebiete:
(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1. PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader .
1
1 Cited Publications
Art. -Nr.: HY-W010712
CAS. Nr.: 109425-51-6
Target:
Forschungsgebiete:
Category:
Monophenols Metabolic Disease Agrostidoideae Extract Phenols Plants Disease Research Fields Triticum aestivum L.
Target:
Art. -Nr.: HY-W008922
CAS. Nr.: 189937-46-0
Target:
Forschungsgebiete:
Forschungsgebiete:
L-Cytidine is the L-configurational form of Cytidine (HY-B0158). L-Cytidine is a pyrimidine nucleoside and a component of RNA. Cytidine regulates glial glutamate cycling, affects cephalin metabolism, catecholamine synthesis and mitochondrial function. L-Cytidine interacts with HSA, which may alter the structure and function of HSA .
Art. -Nr.: HY-145728B
Reinheit: 97.08%
Synonyms: (R/S)-ISIS-2302
Target:
Forschungsgebiete:
(R/S)-Alicaforsen is the racemate of Alicaforsen composed of R and S configurations. Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
Art. -Nr.: HY-160440
CAS. Nr.: 2307718-96-1
Target:
Forschungsgebiete:
rel-VU6021625 is the relative configuration of VU6021625 (HY-160440A). VU6021625 is a potent and selective mAChR M4 antagonist with IC50 values of 0.44 nM and 57 nM for human M4, rat M4, respectively .
Art. -Nr.: HY-148864
Reinheit: 99.95%
Target:
Forschungsgebiete:
JQ1-TCO is the double bond E configuration of JQ1-TCO (HY-148864A). JQ1-TCO is a derivative of JQ1 (HY-13030), an inhibitor of BET. JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo .
Art. -Nr.: HY-W074648
CAS. Nr.: 1239602-35-7
Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .
Target:
L-Guanosine is the L-configuration of Guanosine (HY-N0097). L-Guanosine is a purine nucleoside with anti-herpesvirus activity. L-Guanosine can be used to prepare supramolecular hydrogel .
Target:
Forschungsgebiete:
2'-Deoxy-L-guanosine selectively inhibits D-Thymidine phosphorylation catalyzed by HSV 1 thymidine kinase. 2'-Deoxy-L-guanosine is the L-configuration of 2'-Deoxyguanosine (HY-17563) .
Art. -Nr.: HY-W337569
CAS. Nr.: 188416-29-7
Synonyms: (±)-UK-109496
(±)-Voriconazole ((±)-UK-109496) is a relative configuration of Voriconazole (HY-76200). Voriconazole is an antifungal agent .
Target:
Forschungsgebiete:
(R)-Lactoyl-CoA ((R)-Lactoyl-coenzyme A) is a lactoyl-CoA in which the lactoyl residue has (R)-configuration.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
