Zoledronate disodium
Zoledronate (CGP 42446) disodium is a potent bisphosphonate that effectively inhibits osteoclastogenesis, reducing bone turnover and stabilizing the bone matrix. Zoledronate disodium has demonstrated notable effectiveness in managing Paget's disease of bone by suppressing metabolic activity and alleviating bone pain. Zoledronate disodium is being investigated in the ongoing ZiPP trial for its potential to prevent disease progression in patients with Paget's disease. Zoledronate disodium also exhibits diverse anti-tumor effects in osteosarcoma, further highlighting its multifunctional therapeutic applications.
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- CAS. Nr.: 131654-46-1
- Formel: C5H8N2Na2O7P2
- Molecular Weight:316.05
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 131654-46-1
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Molecular Weight 316.05
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Formel C5H8N2Na2O7P2
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SMILES
O=P(O)(C(CN1C=NC=C1)(P(O[Na])(O[Na])=O)O)O
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Synonyms
CGP 42446 disodium; CGP42446A disodium; ZOL 446 disodium
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Zoledronate disodium Related Classifications
HY-13777C Related Classifications
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