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Cat. No.: HY-106795

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502U83

502U83 is an anti-cancer agent. 502U83 can inhibit DNA and RNA synthesis (IC₅₀ ≈ 30 µM). 502U83 can be used for research on cancers such as leukemia.

For research use only. We do not sell to patients.

CAS No.: 129026-48-8
Formula: C₂₁H₂₅NO₄
Molecular Weight:355.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

502U83 Chemical Structure

CAS No.: 129026-48-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

502U83 is an anti-cancer agent. 502U83 can inhibit DNA and RNA synthesis (IC₅₀ ≈ 30 µM). 502U83 can be used for research on cancers such as leukemia^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 129026-48-8
Molecular Weight 355.43
Formula C₂₁H₂₅NO₄
SMILES

OCC(CO)(C)NCC1=C2C(C=CC=C2)=C(OCCO)C3=CC=CC=C13
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Carter CA, et al. Effects of isomeric 2-(arylmethylamino)-1,3-propanediols (AMAPs) and clinically established agents on macromolecular synthesis in P388 and MCF-7 cells. Invest New Drugs. 1991 May;9(2):125-36. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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